Parvulin-14 Recombinant Protein

ProSci
Product Code: PSI-92-173
Product Group: Recombinant Proteins
Supplier: ProSci
CodeSizePrice
PSI-92-173-0.05mg0.05mg£673.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Target Species: Human
Storage:
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Documents

Further Information

Additional Names:
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4, Parvulin-14, Parvulin-17, Peptidyl-prolyl cis-trans isomerase Pin4, Peptidyl-prolyl cis/trans isomerase EPVH, Rotamase Pin4, PIN4
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4(PIN4) is a peptidyl-prolyl cis/trans isomerase (PPIase) which interacts with NIMA and is vital for cell cycle regulation. PIN4 has 2 different isoforms: PAR14 and PAR17. Furthermore, PIN4 protein binds to double-stranded DNA under physiological salt conditions. PIN4 is involved as a ribosomal RNA processing factor in ribosome biogenesis. The PAR14 binds to tightly bent AT-rich stretches of double-stranded DNA, but PAR17 binds to double-stranded DNA.
Buffer:
Supplied as a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
N-6 His tag
NCBI Gene ID #:
5303
NCBI Official Name:
peptidylprolyl cis/trans isomerase, NIMA-interacting 4
NCBI Official Symbol:
PIN4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
18.8 kD
Protein Accession #:
Q9Y237-2
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
Q9Y237-2