PSGL-1 Recombinant Protein

Product Code: PSI-91-961

Supplier: ProSci

Code	Size	Price

PSI-91-961-0.05mg

0.05mg

£597.00

Quantity:

Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO

Target Species: Mouse

Storage:

Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.

Documents

Datasheet

Further Information

Additional Names:

CLA; CD162; PSGL1; PSGL-1, CD162, SELPLG

Application Note:

This recombinant protein can be used for biological assays. For research use only.

Background:

P-selectin glycoprotein ligand 1 is the high affinitycounter-receptor for P-selectin on expressed on activated endothelial cells and platelets. As such, it plays a critical role in the tethering of these cells to activated platelets or endothelia expressing P-selectin. As cell adhesion molecules, multiple studies have shown that PSGL-1/ P-selectin interaction is required for the normal recruitment of leukocytes during inflammatory reactions, and also participates in hemostatic responses. PSGL-1 can also bind to other two members of the selectin family, E-selectin (endothelial) and L-selectin (leukocyte), but binds best to P-selectin.

Buffer:

Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

Fusion Tag:

C-Fc tag

NCBI Gene ID #:

20345

NCBI Official Name:

selectin, platelet (p-selectin) ligand

NCBI Official Symbol:

Selplg

NCBI Organism:

Mus musculus

Physical State:

Lyophilized

Predicted Molecular Weight:

54.7 kD

Protein Accession #:

Q62170

Purity:

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

Recombinant Protein Sequence:

Thr32-Gly402

Source:

Human Cells

Swissprot #:

Q62170