Toxin B Recombinant Protein

Product Code: PSI-92-498

Supplier: ProSci

Code	Size	Price

PSI-92-498-0.05mg

0.05mg

£753.00

Quantity:

Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO

Target Species: Vibrio species (bacteria)

Storage:

Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.

Documents

Datasheet

Further Information

Additional Names:

Cholera enterotoxin subunit B, Cholera enterotoxin B chain, Cholera enterotoxin gamma chain, Choleragenoid, ctxB, toxB, REF: C1001

Application Note:

This recombinant protein can be used for biological assays. For research use only.

Background:

Cholera toxin is protein complex secreted by the bacterium Vibrio cholerae. It is responsible for the massive, watery diarrhea characteristic of cholera infection. Cholera enterotoxin subunit B (CTXB) pentameric ring directs the A subunit to its target by binding to the GM1 gangliosides present on the surface of the intestinal epithelial cells. It can bind five GM1 gangliosides. It has no toxic activity by itself.

Buffer:

Lyophilized from a 0.2 um filtered solution of 50mM Tris, 200uM NaCl,pH8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

Fusion Tag:

Tag Free

NCBI Gene ID #:

2613962

NCBI Official Name:

cholera enterotoxin subunit B

NCBI Official Symbol:

VC1456

NCBI Organism:

Vibrio cholerae O1 biovar El Tor str. N16961

Physical State:

Lyophilized

Predicted Molecular Weight:

11.8 kD

Protein Accession #:

P01556

Purity:

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

Recombinant Protein Sequence:

Thr32-Gly402

Source:

E. coli

Swissprot #:

P01556