HLA-DP monoclonal antibody, clone SPM421

Abnova Corporation
Product Code: MAB13076
Product Group: Primary Antibodies
CodeSizePrice
MAB13076-100ug100 ug£488.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgG2b, kappa
Antibody Clonality: Monoclonal
Antibody Clone: SPM421
Regulatory Status: RUO
Target Species: Human
Applications:
  • Flow Cytometry
  • Immunofluorescence (IF)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
Store at -20 to -80°C.
Aliquot to avoid repeated freezing and thawing.

Further Information

Antigen Target Species:
Human
Form:
Liquid
Gene Alias:
DPB1|HLA-DP1B
Gene Description:
major histocompatibility complex, class II, DP beta 1
Gene ID:
3115
Gene Name:
HLA-DPB1
Immunogen:
Human non-T/non-B-cell-type acute lymphoblastic leukemia REH6 cell line.
Product Description:
Mouse monoclonal antibody raised against native human HLA-DP.
Protein Accession:
P04440
Recommend Dilutions:
Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL)
Immunofluorescence (0.5-1 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.
Specificity:
Recognizes a non-polymorphic determinant of DP-MHC class II. MHC class II antigens are transmembrane glycoproteins of non-covalently linked alpha (33-35 kDa) and beta (27-30 kDa) chains. It reportedly reacts with B- & non-T, non-B cell lines but not with T- and myeloid cell lines and leukemias. Differential expression of MHC class II antigens on fetal and adult lymphocytes, malignant B cells appears to reflect the stage of cell differentiation which may be useful in the study of lymphoproliferative disorders.
Storage Buffer:
In 10 mM PBS.