IL2RA recombinant monoclonal antibody clone Basiliximab
| Code | Size | Price |
|---|
| RAB00048-200ug | 200 ug | £709.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Caprine (Goat)
Antibody Isotype: IgG1 kappa
Antibody Clonality: Recombinant Antibody
Antibody Clone: Basiliximab
Regulatory Status: RUO
Target Species: Human
Applications:
- Blocking
- Flow Cytometry
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
Store at 4°C for up to 3 months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Aliquot to avoid repeated freezing and thawing.
Further Information
Antigen Target Species:
Human
Form:
Liquid
Gene Alias:
CD25|IDDM10|IL2R|TCGFR
Gene Description:
interleukin 2 receptor, alpha
Gene ID:
3559
Gene Name:
IL2RA
Note:
This is a chimeric antibody created for improved compatibility with existing reagents, assays and techniques.
Preparation Method:
Basiliximab was prepared by immunizing BALB/c mice with CTC 16 cells.
Product Description:
Humanized recombinant monoclonal antibody raised against human IL2RA.
Protein Accession:
P01589
Recommend Dilutions:
Blocking
Flow Cytometry (1 ug/mL)
Immunofluorescence
Immunohistochemistry (5 ug/mL)
Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.
Flow Cytometry (1 ug/mL)
Immunofluorescence
Immunohistochemistry (5 ug/mL)
Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.
Specificity:
Basiliximab recognises the human IL-2R and binds to the epitope (116)ERIYHFV(122) within the extracellular domain of the CD25 subunit- binding is abolished when 2 or more residues within the epitope are mutated. This epitope overlaps with the interaction site of CD25 and IL-2. CD25 is found in the high-affinity IL-2R (alpha beta gamma c)- T cells only express CD25 upon activation. IL-2 binding to IL-2R on T cells modulates proliferation and differentiation.
Storage Buffer:
In PBS, pH 7.2 (0.02% Proclin 300).