3-cis-Hydroxyglibenclamide
| Code | Size | Price |
|---|
| CDX-H0030-M001 | 1 mg | £151.00 |
Quantity:
| CDX-H0030-M005 | 5 mg | £572.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
+4°C
Documents
Further Information
Alternate Names/Synonyms:
3-cis-Hydroxycyclohexyl glyburide; cis-3-Hydroxyglyburide
Appearance:
White to off-white powder.
CAS:
23074-02-4
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Handling Advice:
Keep cool and dry.Protect from light and moisture.
Hazards:
H315, H319, H335
InChi:
InChI=1S/C23H28ClN3O6S/c1-33-21-10-7-16(24)13-20(21)22(29)25-12-11-15-5-8-19(9-6-15)34(31,32)27-23(30)26-17-3-2-4-18(28)14-17/h5-10,13,17-18,28H,2-4,11-12,14H2,1H3,(H,25,29)(H2,26,27,30)/t17-,18+/m0/s1
InChiKey:
VFBAJFAMXTVSQA-ZWKOTPCHSA-N
Long Description:
Chemical. CAS: 23074-02-4. Formula: C23H28ClN3O6S. MW: 510. Synthetic. M2-Metabolite of the antidiabetic compound glyburide. Antidiabetic reagent. Shows 50% hypoglycaemic activity of the parent compound, by increasing insulin secretion. Compound can be used as analytical reference material.
MDL:
MFCD11978021
Molecular Formula:
C23H28ClN3O6S
Molecular Weight:
510
Package Type:
Vial
Precautions:
P280, P305, P351, P338, P337, P313
Product Description:
M2-Metabolite of the antidiabetic compound glyburide. Antidiabetic reagent. Shows 50% hypoglycaemic activity of the parent compound, by increasing insulin secretion. Compound can be used as analytical reference material.
Purity:
>97% (HPLC)
Signal word:
Warning
SMILES:
COC1=C(C(NCCC2=CC=C(S(=O)(NC(N[C@H]3CCC[C@@H](O)C3)=O)=O)C=C2)=O)C=C(Cl)C=C1
Solubility Chemicals:
Sligthly soluble in DMSO or methanol.
Source / Host:
Synthetic.
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
(1) W. Heptner, et al.; Pharmaceut. Res. 5, 215 (1984) | (2) T. Rydberg, et al.; J. Chromatogr. 564, 223 (1991) | (3) T. Rydberg, et al.; Diabetes Care 17, 1026 (1994) | (4) T. Rydberg, et al.; J. Clin. Pharm. Ther. 20, 283 (1995) | (5) T. Rydberg, et al.; Br. J. Clin. Pharm. 43, 373 (1997)
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