CD9

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ProSci
Product Code: PSI-8531
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-8531-0.02mg0.02mg£150.00
Quantity:
PSI-8531-0.1mg0.1mg£449.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
CD9 antibody can be stored at 4C for three months and -20C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of CD9 in (A) human ovary, (B) human uterus, (C) human ovary tumor, and (D) human uterus tumor tissue lysate with CD9 antibody at 1 μg/ml.
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Western blot analysis of CD9 in (A) human ovary, (B) human uterus, (C) human ovary tumor, and (D) human uterus tumor tissue lysate with CD9 antibody at 1 μg/ml.

Documents

Further Information

Additional Names:
CD9 Antibody: CD9 molecule, MIC3, MRP-1, BTCC-1, DRAP-27, TSPAN29, TSPAN-29
Application Note:
CD9 antibody can be used for Western blot at 1 - 2 μg/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Background:
CD9 Antibody: CD9 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Like other tetraspanins, CD9 is a cell surface glycoproteins play a role in many cellular processes including differentiation, adhesion, and signal transduction (1). CD9 expression plays a critical role in the suppression of cancer cell motility and metastasis. In one study, the knockdown of CD9 expression suppressed the metastatic capacity of human breast cancer cells (2), while other results have shown the opposite effect, suggesting that different proteins associated with CD9 account for its abilities to promote or suppress metastasis (3).
Background References:
  • Murayama Y, Oritani K, and Tsutsui S. Novel CD9-targeted therapies in gastric cancer. World J. Gastroenterol. 2015; 21:3206-13.
  • Rappa G, Green TM, Karbanova J, Corbeil D, et al. Tetraspanin CD9 determines invasiveness and tumorigenicity of human breast cancer cells. Oncotarget 2015; 6:7970-91.
  • Zoller M. Tetraspanins: push and pull in suppressing and promoting metastasis. Nat. Rev. Cancer 2009; 9:40-55.
Buffer:
CD9 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Cat: (90%), Bovine: (89%), Mouse: (84%), Rat: (84%), Boar: (78%)
Immunogen:
CD9 antibody was raised against a peptide corresponding to 19 amino acids near the center of human CD9.
NCBI Gene ID #:
928
NCBI Official Name:
CD9
NCBI Official Symbol:
CD9
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Predicted: 25 kDa

Observed: 25 kDa
Protein Accession #:
NP_001760
Protein GI Number:
4502693
Purification:
CD9 Antibody is affinity chromatography purified via peptide column.
Research Area:
Cancer,Cell Cycle
Swissprot #:
P21926
User NOte:
Optimal dilutions for each application to be determined by the researcher.