PLX4032
| Code | Size | Price |
|---|
| SYN-1161-M100 | 100 mg | Enquire |
Quantity:
| SYN-1161-M001 | 1 mg | £69.00 |
Quantity:
| SYN-1161-M005 | 5 mg | £86.00 |
Quantity:
| SYN-1161-M010 | 10 mg | £98.00 |
Quantity:
| SYN-1161-M050 | 50 mg | £315.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
Vemurafenib; RG7204; Zelboraf; RO5185426
Appearance:
Solid.
CAS:
918504-65-1
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS08
Hazards:
H350, H361
InChi:
InChI=1S/C23H18ClF2N3O3S/c1-2-9-33(31,32)29-19-8-7-18(25)20(21(19)26)22(30)17-12-28-23-16(17)10-14(11-27-23)13-3-5-15(24)6-4-13/h3-8,10-12,29H,2,9H2,1H3,(H,27,28)
InChiKey:
GPXBXXGIAQBQNI-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 918504-65-1. Formula: C23H18ClF2N3O3S. MW: 489.9. PLX4032 (Vemurafenib, RG7204, Zelboraf, RO5185426) is a novel and potent inhibitor of B-RafV600E with an IC(50) of 31nM.
Molecular Formula:
C23H18ClF2N3O3S
Molecular Weight:
489.9
Package Type:
Plastic Vial
Precautions:
P201, P202, P281, P308, P313, P405, P501,
Product Description:
PLX4032 (Vemurafenib, RG7204, Zelboraf, RO5185426) is a novel and potent inhibitor of B-RafV600E with an IC(50) of 31nM.
Purity:
>95%
Signal word:
Danger
Solubility Chemicals:
Soluble in DMSO or ethanol.
Transportation:
Non-hazardous
UNSPSC Category:
Protein Kinase Modulators
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
BRAF silencing by short hairpin RNA or chemical blockade by PLX4032 leads to different responses in melanoma and thyroid carcinoma cells: E. Sala, et al.; Mol. Cancer Res. 6, 751 (2008)