Tandutinib
| Code | Size | Price |
|---|
| SYN-1088-M100 | 100 mg | Enquire |
Quantity:
| SYN-1088-M001 | 1 mg | £69.00 |
Quantity:
| SYN-1088-M005 | 5 mg | £86.00 |
Quantity:
| SYN-1088-M010 | 10 mg | £98.00 |
Quantity:
| SYN-1088-M050 | 50 mg | £115.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
CT53518; MLN518
Appearance:
Solid.
CAS:
387867-13-2
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Hazards:
H303, H317, H333
InChi:
InChI=1S/C31H42N6O4/c1-23(2)41-25-10-8-24(9-11-25)34-31(38)37-17-15-36(16-18-37)30-26-20-28(39-3)29(21-27(26)32-22-33-30)40-19-7-14-35-12-5-4-6-13-35/h8-11,20-23H,4-7,12-19H2,1-3H3,(H,34,38)
InChiKey:
UXXQOJXBIDBUAC-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 387867-13-2. Formula: C31H42N6O4. MW: 562.7. Tandutinib inhibits the auto-phosphorylation of FLT3 (FMS-Like Tyrosine kinase-3, IC(50) of 0.22µM), c-KIT and PDGF (platelet-derived growth factor), thereby inhibiting cellular proliferation and inducing apoptosis.
Molecular Formula:
C31H42N6O4
Molecular Weight:
562.7
Package Type:
Plastic Vial
Precautions:
P261, P272, P280, P302, P352, P333, P313, P321, P363, P501
Product Description:
Tandutinib inhibits the auto-phosphorylation of FLT3 (FMS-Like Tyrosine kinase-3, IC(50) of 0.22µM), c-KIT and PDGF (platelet-derived growth factor), thereby inhibiting cellular proliferation and inducing apoptosis.
Purity:
>95%
Signal word:
Warning
Solubility Chemicals:
Soluble in DMSO or ethanol.
Transportation:
Non-hazardous
UNSPSC Category:
Protein Kinase Modulators
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
CT53518, a novel selective FLT3 antagonist for the treatment of acute myelogenous leukemia (AML): L.M. Kelly, et al.; Cancer Cell 1, 421 (2002)
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