SD-169
| Code | Size | Price |
|---|
| SYN-1079-M100 | 100 mg | Enquire |
Quantity:
| SYN-1079-M001 | 1 mg | £69.00 |
Quantity:
| SYN-1079-M005 | 5 mg | £86.00 |
Quantity:
| SYN-1079-M010 | 10 mg | £98.00 |
Quantity:
| SYN-1079-M050 | 50 mg | £291.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
SD169
Appearance:
Solid.
CAS:
1670-87-7
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Hazards:
H303, H317, H333
InChi:
InChI=1S/C9H8N2O/c10-9(12)7-1-2-8-6(5-7)3-4-11-8/h1-5,11H,(H2,10,12)
InChiKey:
GQMYQEAXTITUAE-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 1670-87-7. Formula: C9H8N2O. MW: 160.2. SD169 is an orally available, ATP-competitive, isoenzyme-selective Mitogen-Activated Protein Kinase (MAPK) inhibitor. It is 38 times more potent against p38alpha MAP kinase (IC(50) of 3.2nM) over p38beta MAP kinase (IC(50) of 122nM).
Molecular Formula:
C9H8N2O
Molecular Weight:
160.2
Package Type:
Plastic Vial
Precautions:
P261, P272, P280, P302, P352, P333, P313, P321, P363, P501
Product Description:
SD169 is an orally available, ATP-competitive, isoenzyme-selective Mitogen-Activated Protein Kinase (MAPK) inhibitor. It is 38 times more potent against p38alpha MAP kinase (IC(50) of 3.2nM) over p38beta MAP kinase (IC(50) of 122nM).
Purity:
>95%
Signal word:
Warning
Solubility Chemicals:
Soluble in DMSO or ethanol.
Transportation:
Non-hazardous
UNSPSC Category:
Protein Kinase Modulators
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
Preventive and therapeutic potential of p38 alpha-selective mitogen-activated protein kinase inhibitor in nonobese diabetic mice with type 1 diabetes: S. Medicherla, et al.; J. Pharmacol. Exp. Ther. 318, 99 (2006)
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