PIK-75
| Code | Size | Price |
|---|
| SYN-1067-M100 | 100 mg | Enquire |
Quantity:
| SYN-1067-M001 | 1 mg | £69.00 |
Quantity:
| SYN-1067-M005 | 5 mg | £86.00 |
Quantity:
| SYN-1067-M010 | 10 mg | £98.00 |
Quantity:
| SYN-1067-M050 | 50 mg | £332.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
PIK75
Appearance:
Solid.
CAS:
372196-67-3
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Hazards:
H303, H317, H333
InChi:
InChI=1S/C16H14BrN5O4S/c1-11-3-5-13(22(23)24)7-15(11)27(25,26)20(2)19-9-14-8-18-16-6-4-12(17)10-21(14)16/h3-10H,1-2H3/b19-9+
InChiKey:
QTHCAAFKVUWAFI-DJKKODMXSA-N
Long Description:
Chemical. CAS: 372196-67-3. Formula: C16H14BrN5O4S. MW: 452.3. PIK-75 is a PI3K inhibitor displaying selectivity for the p110alpha isoform (IC(50) of 6nM). PIK-75 blocks the phosphorylation of PKB induced by insulin.
Molecular Formula:
C16H14BrN5O4S
Molecular Weight:
452.3
Package Type:
Plastic Vial
Precautions:
P261, P272, P280, P302, P352, P333, P313, P321, P363, P501
Product Description:
PIK-75 is a PI3K inhibitor displaying selectivity for the p110alpha isoform (IC(50) of 6nM). PIK-75 blocks the phosphorylation of PKB induced by insulin.
Purity:
>95%
Signal word:
Warning
Solubility Chemicals:
Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol.
Transportation:
Non-hazardous
UNSPSC Category:
Protein Kinase Modulators
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
Phosphoinositide-3-kinases (PI3Ks): combined comparative modeling and 3D-QSAR to rationalize the inhibition of p110alpha: R. Frederick & W.A. Denny; J. Chem. Inf. Model 48, 629 (2008)