GW-441756
| Code | Size | Price |
|---|
| SYN-1044-M100 | 100 mg | Enquire |
Quantity:
| SYN-1044-M001 | 1 mg | £80.00 |
Quantity:
| SYN-1044-M005 | 5 mg | £127.00 |
Quantity:
| SYN-1044-M010 | 10 mg | £145.00 |
Quantity:
| SYN-1044-M050 | 50 mg | £543.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
GW441756
Appearance:
Solid.
CAS:
504433-23-2
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Hazards:
H303, H317, H333
InChi:
InChI=1S/C17H13N3O/c1-20-10-11(12-5-2-3-7-15(12)20)9-13-16-14(19-17(13)21)6-4-8-18-16/h2-10H,1H3,(H,19,21)/b13-9-
InChiKey:
NXNQLECPAXXYTR-LCYFTJDESA-N
Long Description:
Chemical. CAS: 504433-23-2. Formula: C17H13N3O. MW: 275.3. GW441756 is an orally active, potent and highly selective TrkA tyrosine kinase inhibitor (IC(50) of 2nM). It specifically blocks TrkA-induced cell death in a dose-dependent manner.
Molecular Formula:
C17H13N3O
Molecular Weight:
275.3
Package Type:
Plastic Vial
Precautions:
P261, P272, P280, P302, P352, P333, P313, P321, P363, P501
Product Description:
GW441756 is an orally active, potent and highly selective TrkA tyrosine kinase inhibitor (IC(50) of 2nM). It specifically blocks TrkA-induced cell death in a dose-dependent manner.
Purity:
>95%
Signal word:
Warning
Solubility Chemicals:
Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol.
Transportation:
Non-hazardous
UNSPSC Category:
Protein Kinase Modulators
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
Dorsomorphin stimulates neurite outgrowth in PC12 cells via activation of a protein kinase A-dependent MEK-ERK1/2 signaling pathway: T.A. Kudo, et al.; Genes Cells 16, 1121 (2011)
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