Vandetanib
| Code | Size | Price |
|---|
| SYN-1090-M100 | 100 mg | Enquire |
Quantity:
| SYN-1090-M001 | 1 mg | £80.00 |
Quantity:
| SYN-1090-M005 | 5 mg | £104.00 |
Quantity:
| SYN-1090-M010 | 10 mg | £127.00 |
Quantity:
| SYN-1090-M050 | 50 mg | £303.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
ZD6474; Zactima; Vandetanib
Appearance:
Solid.
CAS:
443913-73-3
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Hazards:
H303, H317, H333
InChi:
InChI=1S/C22H24BrFN4O2/c1-28-7-5-14(6-8-28)12-30-21-11-19-16(10-20(21)29-2)22(26-13-25-19)27-18-4-3-15(23)9-17(18)24/h3-4,9-11,13-14H,5-8,12H2,1-2H3,(H,25,26,27)
InChiKey:
UHTHHESEBZOYNR-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 443913-73-3. Formula: C22H24BrFN4O2. MW: 475.4. Vandetanib is a tyrosine kinase inhibitor that targets vascular endothelial growth factor receptor (VEGFR, IC(50) of 40nM) and the epidermal growth factor receptor (EGFR).
Molecular Formula:
C22H24BrFN4O2
Molecular Weight:
475.4
Package Type:
Plastic Vial
Precautions:
P261, P272, P280, P302, P352, P333, P313, P321, P363, P501
Product Description:
Vandetanib is a tyrosine kinase inhibitor that targets vascular endothelial growth factor receptor (VEGFR, IC(50) of 40nM) and the epidermal growth factor receptor (EGFR).
Purity:
>95%
Signal word:
Warning
Solubility Chemicals:
Soluble in DMSO or ethanol.
Transportation:
Non-hazardous
UNSPSC Category:
Protein Kinase Modulators
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
ZD6474, an orally available inhibitor of KDR tyrosine kinase activity, efficiently blocks oncogenic RET kinases: F. Carlomagno, et al.; Cancer Res. 62, 7284 (2002)
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