Regorafenib
| Code | Size | Price |
|---|
| SYN-1169-M100 | 100 mg | Enquire |
Quantity:
| SYN-1169-M001 | 1 mg | £104.00 |
Quantity:
| SYN-1169-M005 | 5 mg | £162.00 |
Quantity:
| SYN-1169-M010 | 10 mg | £244.00 |
Quantity:
| SYN-1169-M050 | 50 mg | £771.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
BAY-73-4506
Appearance:
Solid.
CAS:
755037-03-7
EClass:
32160000
Form (Short):
liquid
InChi:
InChI=1S/C21H15ClF4N4O3/c1-27-19(31)18-10-13(6-7-28-18)33-12-3-5-17(16(23)9-12)30-20(32)29-11-2-4-15(22)14(8-11)21(24,25)26/h2-10H,1H3,(H,27,31)(H2,29,30,32)
InChiKey:
FNHKPVJBJVTLMP-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 755037-03-7. Formula: C21H15ClF4N4O3. MW: 482.8. Regorafenib (BAY 73-4506, Fluoro-Sorafenib) is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFR, Kit, RET and Raf-1 with IC(50) values of 13, 4.2, 46, 22, 7, 1.5 and 2.5nM, respectively.
Molecular Formula:
C21H15ClF4N4O3
Molecular Weight:
482.8
Package Type:
Plastic Vial
Product Description:
Regorafenib (BAY 73-4506, Fluoro-Sorafenib) is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFR, Kit, RET and Raf-1 with IC(50) values of 13, 4.2, 46, 22, 7, 1.5 and 2.5nM, respectively.
Purity:
>95%
Solubility Chemicals:
Soluble in DMSO or ethanol.
Transportation:
Non-hazardous
UNSPSC Category:
Protein Kinase Modulators
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
Regorafenib (BAY 73-4506): a new oral multikinase inhibitor of angiogenic, stromal and oncogenic receptor tyrosine kinases with potent preclinical antitumor activity: S.M. Wilhelm, et al.; Int. J. Cancer 129, 245 (2011)