LY2784544
| Code | Size | Price |
|---|
| SYN-1196-M100 | 100 mg | Enquire |
Quantity:
| SYN-1196-M001 | 1 mg | £115.00 |
Quantity:
| SYN-1196-M005 | 5 mg | £197.00 |
Quantity:
| SYN-1196-M010 | 10 mg | £303.00 |
Quantity:
| SYN-1196-M050 | 50 mg | £1,053.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
LY-2784544
Appearance:
Solid.
CAS:
1229236-86-5
EClass:
32160000
Form (Short):
liquid
InChi:
InChI=1S/C23H25ClFN7O/c1-14-9-21(29-28-14)27-22-11-17(13-31-5-7-33-8-6-31)23-26-15(2)20(32(23)30-22)10-16-3-4-18(24)12-19(16)25/h3-4,9,11-12H,5-8,10,13H2,1-2H3,(H2,27,28,29,30)
InChiKey:
SQSZANZGUXWJEA-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 1229236-86-5. Formula: C23H25ClFN7O. MW: 469.9. LY2784544 is a potent JAK2 inhibitor with IC(50) of 3nM, effective in JAK2V617F, 8- and 20-fold selective versus JAK1 and JAK3. Phase 2.
Molecular Formula:
C23H25ClFN7O
Molecular Weight:
469.9
Package Type:
Plastic Vial
Product Description:
LY2784544 is a potent JAK2 inhibitor with IC(50) of 3nM, effective in JAK2V617F, 8- and 20-fold selective versus JAK1 and JAK3. Phase 2.
Purity:
>95%
Solubility Chemicals:
Soluble in DMSO or ethanol.
Transportation:
Non-hazardous
UNSPSC Category:
Protein Kinase Modulators
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
Discovery and characterization of LY2784544, a small-molecule tyrosine kinase inhibitor of JAK2V617F: L. Ma, et al.; Blood Cancer J. 3, e109 (2013)
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