Foretinib
| Code | Size | Price |
|---|
| SYN-1129-M100 | 100 mg | Enquire |
Quantity:
| SYN-1129-M001 | 1 mg | £133.00 |
Quantity:
| SYN-1129-M005 | 5 mg | £197.00 |
Quantity:
| SYN-1129-M010 | 10 mg | £350.00 |
Quantity:
| SYN-1129-M050 | 50 mg | £1,006.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
GSK-1363089; EXEL-2880
Appearance:
Solid.
CAS:
849217-64-7
EClass:
32160000
Form (Short):
liquid
InChi:
InChI=1S/C34H34F2N4O6/c1-43-30-20-25-27(21-31(30)45-16-2-13-40-14-17-44-18-15-40)37-12-9-28(25)46-29-8-7-24(19-26(29)36)39-33(42)34(10-11-34)32(41)38-23-5-3-22(35)4-6-23/h3-9,12,19-21H,2,10-11,13-18H2,1H3,(H,38,41)(H,39,42)
InChiKey:
CXQHYVUVSFXTMY-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 849217-64-7. Formula: C34H34F2N4O6. MW: 632.7. Foretinib is a novel MET and VEGFR2 kinase inhibitor with IC(50) values of 0.4 and 0.8nM for MET and VEGFR2 respectively.
Molecular Formula:
C34H34F2N4O6
Molecular Weight:
632.7
Package Type:
Plastic Vial
Product Description:
Foretinib is a novel MET and VEGFR2 kinase inhibitor with IC(50) values of 0.4 and 0.8nM for MET and VEGFR2 respectively.
Purity:
>95%
Solubility Chemicals:
Soluble in DMSO.
Transportation:
Non-hazardous
UNSPSC Category:
Protein Kinase Modulators
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
Foretinib (GSK1363089), an orally available multikinase inhibitor of c-Met and VEGFR-2, blocks proliferation, induces anoikis, and impairs ovarian cancer metastasis: M. Zillhardt, et al.; Clin. Cancer Res. 17, 4042 (2011)