BMS-599626
| Code | Size | Price |
|---|
| SYN-1142-M100 | 100 mg | Enquire |
Quantity:
| SYN-1142-M001 | 1 mg | £133.00 |
Quantity:
| SYN-1142-M005 | 5 mg | £203.00 |
Quantity:
| SYN-1142-M010 | 10 mg | £332.00 |
Quantity:
| SYN-1142-M050 | 50 mg | £1,029.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
AC-480; BMS599626
Appearance:
Solid.
CAS:
714971-09-2
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Hazards:
H303, H317, H333
InChi:
InChI=1S/C27H27FN8O3/c1-17-23(34-27(37)39-15-22-14-38-8-7-29-22)13-36-25(17)26(30-16-32-36)33-21-5-6-24-19(10-21)11-31-35(24)12-18-3-2-4-20(28)9-18/h2-6,9-11,13,16,22,29H,7-8,12,14-15H2,1H3,(H,34,37)(H,30,32,33)/t22-/m0/s1
InChiKey:
LUJZZYWHBDHDQX-QFIPXVFZSA-N
Long Description:
Chemical. CAS: 714971-09-2. Formula: C27H27FN8O3. MW: 530.6. BMS-599626 is an orally bioavailable, highly selective and potent pan-HER kinase inhibitor. It inhibits HER1 and HER2 with IC(50) values of 20 and 30nM, respectively.
Molecular Formula:
C27H27FN8O3
Molecular Weight:
530.6
Package Type:
Plastic Vial
Precautions:
P261, P272, P280, P302, P352, P333, P313, P321, P363, P501
Product Description:
BMS-599626 is an orally bioavailable, highly selective and potent pan-HER kinase inhibitor. It inhibits HER1 and HER2 with IC(50) values of 20 and 30nM, respectively.
Purity:
>95%
Signal word:
Warning
Solubility Chemicals:
Soluble in DMSO or ethanol.
Transportation:
Non-hazardous
UNSPSC Category:
Protein Kinase Modulators
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
Preclinical antitumor activity of BMS-599626, a pan-HER kinase inhibitor that inhibits HER1/HER2 homodimer and heterodimer signaling: T.W. Wong, et al.; Clin. Cancer Res. 12, 6186 (2006)
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