PIK-93
| Code | Size | Price |
|---|
| SYN-1066-M100 | 100 mg | Enquire |
Quantity:
| SYN-1066-M001 | 1 mg | £133.00 |
Quantity:
| SYN-1066-M005 | 5 mg | £209.00 |
Quantity:
| SYN-1066-M010 | 10 mg | £315.00 |
Quantity:
| SYN-1066-M050 | 50 mg | £1,234.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
PIK93
Appearance:
Solid.
CAS:
593960-11-3
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Hazards:
H303, H317, H333
InChi:
InChI=1S/C14H16ClN3O4S2/c1-8-13(23-14(17-8)18-9(2)20)10-3-4-11(15)12(7-10)24(21,22)16-5-6-19/h3-4,7,16,19H,5-6H2,1-2H3,(H,17,18,20)
InChiKey:
JFVNFXCESCXMBC-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 593960-11-3. Formula: C14H16ClN3O4S2. MW: 389.9. PIK-93 selectively inhibits the type III PI 4-kinase beta enzyme (IC(50) of 19nM). It has also been shown to have activity on PI3Kalpha with an IC(50) of 39nM.
Molecular Formula:
C14H16ClN3O4S2
Molecular Weight:
389.9
Package Type:
Plastic Vial
Precautions:
P261, P272, P280, P302, P352, P333, P313, P321, P363, P501
Product Description:
PIK-93 selectively inhibits the type III PI 4-kinase beta enzyme (IC(50) of 19nM). It has also been shown to have activity on PI3Kalpha with an IC(50) of 39nM.
Purity:
>95%
Signal word:
Warning
Solubility Chemicals:
Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol.
Transportation:
Non-hazardous
UNSPSC Category:
Protein Kinase Modulators
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
Discovery of drug-resistant and drug-sensitizing mutations in the oncogenic PI3K isoform p110 alpha: E.R. Zunder, et al.; Cancer Cell 14, 180 (2008)
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