TG101209

AdipoGen Life Sciences
Product Code: SYN-1103
CodeSizePrice
SYN-1103-M100100 mgEnquire
Quantity:
SYN-1103-M0011 mg£145.00
Quantity:
SYN-1103-M0055 mg£221.00
Quantity:
SYN-1103-M01010 mg£350.00
Quantity:
SYN-1103-M05050 mg£1,053.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
-20°C

Images

1 / 1
Chemical Structure

Chemical Structure

Further Information

Alternate Names/Synonyms:
TG-101209
Appearance:
Solid.
CAS:
936091-14-4
EClass:
32160000
Form (Short):
liquid
InChi:
InChI=1S/C26H35N7O2S/c1-19-18-27-25(29-20-9-11-22(12-10-20)33-15-13-32(5)14-16-33)30-24(19)28-21-7-6-8-23(17-21)36(34,35)31-26(2,3)4/h6-12,17-18,31H,13-16H2,1-5H3,(H2,27,28,29,30)
InChiKey:
JVDOKQYTTYUYDV-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 936091-14-4. Formula: C26H35N7O2S. MW: 509.7. TG101209 is a potent, small molecule JAK2-selective kinase inhibitor with IC(50) values of 6, 25, 17 and 169nM for JAK2, FLT3, RET and JAK3.
Molecular Formula:
C26H35N7O2S
Molecular Weight:
509.7
Package Type:
Plastic Vial
Product Description:
TG101209 is a potent, small molecule JAK2-selective kinase inhibitor with IC(50) values of 6, 25, 17 and 169nM for JAK2, FLT3, RET and JAK3.
Purity:
>95%
Solubility Chemicals:
Soluble in DMSO or ethanol.
Transportation:
Non-hazardous
UNSPSC Category:
Protein Kinase Modulators
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.

References

TG101209, a small molecule JAK2-selective kinase inhibitor potently inhibits myeloproliferative disorder-associated JAK2V617F and MPLW515L/K mutations: A. Pardanani, et al.; Leukemia 21, 1658 (2007)

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