CEP-33779
| Code | Size | Price |
|---|
| SYN-1156-M100 | 100 mg | Enquire |
Quantity:
| SYN-1156-M050 | 50 mg | Enquire |
Quantity:
| SYN-1156-M001 | 1 mg | £180.00 |
Quantity:
| SYN-1156-M005 | 5 mg | £291.00 |
Quantity:
| SYN-1156-M010 | 10 mg | £461.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
CEP33779
Appearance:
Solid.
CAS:
1346168-57-7
EClass:
32160000
Form (Short):
liquid
InChi:
InChI=1S/C24H26N6O2S/c1-28-13-15-29(16-14-28)20-6-3-5-19(17-20)25-24-26-23-22(7-4-12-30(23)27-24)18-8-10-21(11-9-18)33(2,31)32/h3-12,17H,13-16H2,1-2H3,(H,25,27)
InChiKey:
RFZKSQIFOZZIAQ-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 1346168-57-7. Formula: C24H26N6O2S. MW: 462.6. CEP-33779 is a highly selective, orally active inhibitor for JAK2 with an IC(50) of 1.8nM in enzyme and 61nM in cell activity. It inhibits JAK3 with an IC(50) of 150nM.
Molecular Formula:
C24H26N6O2S
Molecular Weight:
462.6
Package Type:
Plastic Vial
Product Description:
CEP-33779 is a highly selective, orally active inhibitor for JAK2 with an IC(50) of 1.8nM in enzyme and 61nM in cell activity. It inhibits JAK3 with an IC(50) of 150nM.
Purity:
>95%
Solubility Chemicals:
Soluble in DMSO or ethanol.
Transportation:
Non-hazardous
UNSPSC Category:
Protein Kinase Modulators
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
A highly selective, orally active inhibitor of Janus kinase 2, CEP-33779, ablates disease in two mouse models of rheumatoid arthritis: K.L. Stump, et al.; Arthritis Res. Ther. 13, R68 (2011)
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