AMG-25
| Code | Size | Price |
|---|
| SYN-1125-M100 | 100 mg | Enquire |
Quantity:
| SYN-1125-M050 | 50 mg | Enquire |
Quantity:
| SYN-1125-M001 | 1 mg | £233.00 |
Quantity:
| SYN-1125-M005 | 5 mg | £590.00 |
Quantity:
| SYN-1125-M010 | 10 mg | £900.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
AMG25
Appearance:
Solid.
CAS:
1003311-62-3
EClass:
32160000
Form (Short):
liquid
InChi:
InChI=1S/C23H17N5O2/c1-14-8-10-28(18-5-2-15(3-6-18)21-25-9-11-30-21)22(29)20(14)16-4-7-19-17(12-16)13-26-23(24)27-19/h2-13H,1H3,(H2,24,26,27)
InChiKey:
IGFSMGCBFTXTJK-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 1003311-62-3. Formula: C23H17N5O2. MW: 395.4. AMG-25 exhibits potent inhibition of c-Kit with greater than 200-fold selectivity over KDR, p38, Lck and Src.
Molecular Formula:
C23H17N5O2
Molecular Weight:
395.4
Package Type:
Plastic Vial
Product Description:
AMG-25 exhibits potent inhibition of c-Kit with greater than 200-fold selectivity over KDR, p38, Lck and Src.
Purity:
>95%
Solubility Chemicals:
Soluble in DMSO.
Transportation:
Non-hazardous
UNSPSC Category:
Protein Kinase Modulators
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
Discovery of aryl aminoquinazoline pyridones as potent, selective, and orally efficacious inhibitors of receptor tyrosine kinase c-Kit: E. Hu, et al.; J. Med. Chem. 51, 3065 (2008)
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