CX-6258
| Code | Size | Price |
|---|
| SYN-1182-M100 | 100 mg | Enquire |
Quantity:
| SYN-1182-M050 | 50 mg | Enquire |
Quantity:
| SYN-1182-M001 | 1 mg | £233.00 |
Quantity:
| SYN-1182-M005 | 5 mg | £385.00 |
Quantity:
| SYN-1182-M010 | 10 mg | £549.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
CX6258
Appearance:
Solid.
CAS:
1202916-90-2
EClass:
32160000
Form (Short):
liquid
InChi:
InChI=1S/C26H24ClN3O3/c1-29-10-3-11-30(13-12-29)26(32)18-5-2-4-17(14-18)24-9-7-20(33-24)16-22-21-15-19(27)6-8-23(21)28-25(22)31/h2,4-9,14-16H,3,10-13H2,1H3,(H,28,31)/b22-16+
InChiKey:
KGBPLKOPSFDBOX-CJLVFECKSA-N
Long Description:
Chemical. CAS: 1202916-90-2. Formula: C26H24ClN3O3. MW: 461.9. CX6258 is a potent inhibitor of Pim-1, Pim-2 and Pim-3 with IC(50) values of 5, 25 and 16nM, respectively.
Molecular Formula:
C26H24ClN3O3
Molecular Weight:
461.9
Package Type:
Plastic Vial
Product Description:
CX6258 is a potent inhibitor of Pim-1, Pim-2 and Pim-3 with IC(50) values of 5, 25 and 16nM, respectively.
Purity:
>95%
Solubility Chemicals:
Soluble in DMSO.
Transportation:
Non-hazardous
UNSPSC Category:
Protein Kinase Modulators
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
CX-4945, an orally bioavailable selective inhibitor of protein kinase CK2, inhibits prosurvival and angiogenic signaling and exhibits antitumor efficacy: A. Siddiqui-Jain, et al.; Cancer Res. 70, 10288 (2010) | Discovery of CX-6258. A Potent, Selective, and Orally Efficacious pan-Pim Kinases Inhibitor: M. Haddach, et al.; ACS Med. Chem. Lett. 3, 135 (2011)
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