CH4987655

AdipoGen Life Sciences
Product Code: SYN-1188
CodeSizePrice
SYN-1188-M100100 mgEnquire
Quantity:
SYN-1188-M05050 mgEnquire
Quantity:
SYN-1188-M0011 mg£233.00
Quantity:
SYN-1188-M0055 mg£590.00
Quantity:
SYN-1188-M01010 mg£848.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
-20°C

Images

1 / 1
Chemical Structure

Chemical Structure

Further Information

Alternate Names/Synonyms:
RO4987655
Appearance:
Solid.
CAS:
874101-00-5
EClass:
32160000
Form (Short):
liquid
InChi:
InChI=1S/C20H19F3IN3O5/c21-14-9-12(24)3-4-15(14)25-19-13(20(30)26-31-7-5-28)8-11(17(22)18(19)23)10-27-16(29)2-1-6-32-27/h3-4,8-9,25,28H,1-2,5-7,10H2,(H,26,30)
InChiKey:
FIMYFEGKMOCQKT-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 874101-00-5. Formula: C20H19F3IN3O5. MW: 565.3. CH4987655 (RO4987655) is an orally active and highly selective small-molecule MEK inhibitor with an in vitro IC(50) of 5.2nM.
Molecular Formula:
C20H19F3IN3O5
Molecular Weight:
565.3
Package Type:
Plastic Vial
Product Description:
CH4987655 (RO4987655) is an orally active and highly selective small-molecule MEK inhibitor with an in vitro IC(50) of 5.2nM.
Purity:
>95%
Solubility Chemicals:
Soluble in DMSO.
Transportation:
Non-hazardous
UNSPSC Category:
Protein Kinase Modulators
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.

References

Safety, tolerability, pharmacokinetics and pharmacodynamics following 4 weeks' treatment with empagliflozin once daily in patients with type 2 diabetes: T. Heise, et al.; Diabetes Obes. Metab. 15, 613 (2013)

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