Takeda-6d
| Code | Size | Price |
|---|
| SYN-1168-M100 | 100 mg | Enquire |
Quantity:
| SYN-1168-M050 | 50 mg | Enquire |
Quantity:
| SYN-1168-M001 | 1 mg | £238.00 |
Quantity:
| SYN-1168-M005 | 5 mg | £461.00 |
Quantity:
| SYN-1168-M010 | 10 mg | £719.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
Takeda 6d
Appearance:
Solid.
CAS:
1125632-93-0
EClass:
32160000
Form (Short):
liquid
InChi:
InChI=1S/C27H19ClFN5O3S/c28-22-16(2-1-3-17(22)27(13-30)10-11-27)24(36)31-20-12-15(6-7-18(20)29)37-21-9-8-19-25(33-21)38-26(32-19)34-23(35)14-4-5-14/h1-3,6-9,12,14H,4-5,10-11H2,(H,31,36)(H,32,34,35)
InChiKey:
MDPMAXSABUPRJI-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 1125632-93-0. Formula: C27H19ClFN5O3S. MW: 548. Takeda-6d has potent inhibitory activity in both B-RAF with an IC(50) of 7.0nM and VEGFR2 with an IC(50) of 2.2nM.
Molecular Formula:
C27H19ClFN5O3S
Molecular Weight:
548
Package Type:
Plastic Vial
Product Description:
Takeda-6d has potent inhibitory activity in both B-RAF with an IC(50) of 7.0nM and VEGFR2 with an IC(50) of 2.2nM.
Purity:
>95%
Solubility Chemicals:
Soluble in DMSO.
Transportation:
Non-hazardous
UNSPSC Category:
Protein Kinase Modulators
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
Design and synthesis of novel DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors. 1. Exploration of [5,6]-fused bicyclic scaffolds: M. Okaniwa, et al.; J. Med. Chem. 55, 3452 (2012)