GNE-477
| Code | Size | Price |
|---|
| SYN-1148-M100 | 100 mg | Enquire |
Quantity:
| SYN-1148-M050 | 50 mg | Enquire |
Quantity:
| SYN-1148-M001 | 1 mg | £238.00 |
Quantity:
| SYN-1148-M005 | 5 mg | £461.00 |
Quantity:
| SYN-1148-M010 | 10 mg | £643.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
GNE477
Appearance:
Solid.
CAS:
1032754-81-6
EClass:
32160000
Form (Short):
liquid
InChi:
InChI=1S/C21H28N8O3S2/c1-14-16(13-27-3-5-29(6-4-27)34(2,30)31)33-18-17(14)25-19(15-11-23-21(22)24-12-15)26-20(18)28-7-9-32-10-8-28/h11-12H,3-10,13H2,1-2H3,(H2,22,23,24)
InChiKey:
AKKCGLXULFRAET-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 1032754-81-6. Formula: C21H28N8O3S2. MW: 504.6. GNE 477 is a potent and efficacious dual PI3K/mTOR inhibitor with an IC(50) value of 4nM and 21nM respectively.
Molecular Formula:
C21H28N8O3S2
Molecular Weight:
504.6
Package Type:
Plastic Vial
Product Description:
GNE 477 is a potent and efficacious dual PI3K/mTOR inhibitor with an IC(50) value of 4nM and 21nM respectively.
Purity:
>95%
Solubility Chemicals:
Soluble in DMSO.
Transportation:
Non-hazardous
UNSPSC Category:
Protein Kinase Modulators
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
Identification of GNE-477, a potent and efficacious dual PI3K/mTOR inhibitor: T.P. Heffron, et al.; Bioorg. Med. Chem. Lett. 20, 2408 (2010)
Related Products
| Product Name | Product Code | Supplier | GNE-490 | SYN-1114 | AdipoGen Life Sciences | Summary Details | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| GNE-493 | SYN-1115 | AdipoGen Life Sciences | Summary Details | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||