7-O-Methylaloeresin A

AdipoGen Life Sciences
Product Code: AG-CN2-0491
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AG-CN2-0491-M0011 mg£105.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
Ambient
Storage:
-20°C

Images

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Chemical Structure

Chemical Structure

Further Information

Alternate Names/Synonyms:
2-Acetonyl-8-C-beta-D[2'-O-(E)-4-hydroxycinnamoyl]glucopyranosyl-7-methoxy-5-methylchromone
Appearance:
Amorphous yellow solid.
CAS:
329361-25-3
EClass:
32160000
Form (Short):
solid
Handling Advice:
Protect from light.
InChi:
InChI=1S/C29H30O11/c1-14-10-20(37-3)24(27-23(14)19(33)12-18(38-27)11-15(2)31)28-29(26(36)25(35)21(13-30)39-28)40-22(34)9-6-16-4-7-17(32)8-5-16/h4-10,12,21,25-26,28-30,32,35-36H,11,13H2,1-3H3/b9-6+/t21-,25-,26+,28+,29-/m1/s1
InChiKey:
WRLXHKDQSQMWSH-ZTUNSOAWSA-N
Long Description:
Chemical. CAS: 329361-25-3. Formula: C29H30O11. MW: 554.5. Isolated from Aloe vera. Metabolite of aloesin. Potent antioxidant (DPPH assay). Antibiotic. Antifungal. Moderate BACE inhibitor.
MDL:
MFCD31560826
Molecular Formula:
C29H30O11
Molecular Weight:
554.5
Package Type:
Vial
Product Description:
Metabolite of aloesin. Potent antioxidant (DPPH assay). Antibiotic. Antifungal. Moderate BACE inhibitor.
Purity:
>95% (HPLC)
SMILES:
OC1=CC=C(/C=C/C(O[C@H]2[C@H](C3=C(OC)C=C(C)C4=C3OC(CC(C)=O)=CC4=O)O[C@H](CO)[C@@H](O)[C@@H]2O)=O)C=C1
Solubility Chemicals:
Soluble in DMSO, ethanol or methanol.
Source / Host:
Isolated from Aloe vera.
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.

References

Metabolism of aloesin and related compounds by human intestinal bacteria: a bacterial cleavage of the C-glucosyl bond and the subsequent reduction of the acetonyl side chain: Q.M. Che, et al.; Chem. Pharm. Bull. (Tokyo) 39, 704 (1991) | 7-O-methylaloeresin A - a new chromone glycoside from Commiphora socotrana: T. Blitzke, et al.; Nat. Prod. Lett. 15, 27 (2001) | Antioxidant, free radical scavenging and anti-inflammatory effects of aloesin derivatives in Aloe vera: A. Yagi, et al.; Planta Med. 68, 957 (2002) | Active constituents from Aloe arborescens as BACE inhibitors: B. Gao, et al.; Yao Xue Xue Bao 41, 1000 (2006) | In vitro antimicrobial and antioxidant activities of anthrone and chromone from the latex of Aloe harlana Reynolds: G. Asamenew, et al.; Phytother. Res. 25, 1756 (2011) | Phytochemical constituents and in vitro radical scavenging activity of different Aloe species: L. Pucini, et al.; Food Chem. 170, 501 (2014)