Anti-Human CD43 Monoclonal Antibody, Unconjugated Clone MEM-59

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Diaclone
Product Code: 853.243.020
Product Group: Primary Antibodies
Supplier: Diaclone
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853.243.020100ug/100ul£375.00
Quantity:
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Overview

Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: MEM-59
Regulatory Status: RUO
Target Species: Human
Applications:
  • Flow Cytometry
  • Immunohistochemistry (IHC)
  • Immunoprecipitation (IP)
  • Western Blot (WB)
Storage:
Store at +2-8°C. For longer storage, freeze aliquots

Documents

Further Information

Antigen:
CD43
Antigen Synonyms:
GPL115
Conjugate:
Purified
Format:
Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Immunisation:
Human T lymphocytes
Reactivity:
Human
Research Area:
Non Lineage Markers,CD Markers
Specificity:
Recognizes neuraminidase-sensitive epitope on CD43 (Leukosialin), a 95-135 kDa type I transmembrane glycoprotein (mucin-type) which is involved in lymphocyte activation
Working Dilution:
We recommend that each laboratory determine an optimum working titre for use in its particular application
Workshop:
IV,V,VI

References

  1. Alvarado M, et al, Eur J Immunol.,1995; 25(4):1051-5. MEM-59 monoclonal antibody detects a CD43 epitope involved in lymphocyte activation.. https://www.ncbi.nlm.nih.gov/pubmed/7537669
  2. Cermak L, et al, J Biol Chem., 2002 8;277(10):7955-61. Molecular mechanisms involved in CD43-mediated apoptosis of TF-1 cells. Roles of transcription Daxx expression, and adhesion molecules.. https://www.ncbi.nlm.nih.gov/pubmed/11773067
  3. Deckert M, et al,Eur J Immunol.,1992;Nov;22(11):2943-7.. CD59 molecule: a second ligand for CD2 in T cell adhesion.. https://www.ncbi.nlm.nih.gov/pubmed/1385156
  4. Leucocyte Typing IV. Knapp W et al. (Eds.), Oxford University Press (1989).. .
  5. Leucocyte Typing V. Schlossman S. et al. (Eds.), Oxford University Press (1995).. .
  6. Leucocyte Typing VI. Kishimoto T. et al. (Eds.), Garland Publishing Inc. (1997).. .
  7. Stefanova I, et al, Mol Immunol.,1989;26(2):153-61. Characterization of a broadly expressed human leucocyte surface antigen MEM-43 anchored in membrane through phosphatidylinositol.. https://www.ncbi.nlm.nih.gov/pubmed/2918859
  8. Stefanova I, et al,Folia Biol (Praha). 1988;34(4):255-65.. Characterization of a 95 kDa human leucocyte sialoglycoprotein: its identity with CD43, gpL115, leukosialin and sialophorin.. https://www.ncbi.nlm.nih.gov/pubmed/2467832