Macrophage monoclonal antibody, clone LN-5

Abnova Corporation
Product Code: MAB14660
Product Group: Primary Antibodies
CodeSizePrice
MAB14660-100ug100 ug£488.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgM, kappa
Antibody Clonality: Monoclonal
Antibody Clone: LN-5
Regulatory Status: RUO
Target Species: Human
Applications:
  • Flow Cytometry
  • Immunofluorescence (IF)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
In PBS.

Further Information

Antigen Target Species:
Human
Form:
Liquid
Immunogen:
Human peripheral blood mononuclear cells.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Product Description:
Mouse monoclonal antibody raised against human macrophage.
Recommend Dilutions:
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.1-0.2 ug/mL for 30 min at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at
Specificity:
This monoclonal antibody stains the cytoplasm of macrophages and histiocytes in hematopoietic organs, Kupffer's cells of the liver and Langerhan's cells of the skin. LN-5 selectively stains human sebaceous glands in formalin-fixed, paraffin-embedded skin samples. Undifferentiated sebocyte progenitors are negative, and only sebocytes from the onset of their differentiation reveal positive cytoplasmic staining. Since there are very few selective and easy-to-use markers of sebaceous glands, LN-5 antibody can offer a simple and relatively specific way to detect human sebocytes from the onset of their.
Storage Buffer:
In 10 mM PBS (0.05% sodium azide).

References

  • https://www.ncbi.nlm.nih.gov/pubmed/22763963
  • https://www.ncbi.nlm.nih.gov/pubmed/01647137