Thioglycine
| Code | Size | Price |
|---|
| AG-CR1-3530-M001 | 1 mg | £80.00 |
Quantity:
| AG-CR1-3530-M005 | 5 mg | £290.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
-20°C
Storage:
Short Term: +4°C. Long Term: -20°C
Documents
Further Information
Alternate Names/Synonyms:
2-Aminoethanethioic S-acid; Aminothioacetic acid
Appearance:
White solid.
CAS:
758-10-1
EClass:
32160000
Form (Short):
liquid
Handling Advice:
Protect from light.
InChi:
InChI=1S/C2H5NOS/c3-1-2(4)5/h1,3H2,(H,4,5)
InChiKey:
CYFJIBWZIQDUSZ-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 758-10-1. Formula: C2H5NOS. MW: 91.1. Synthetic. Non-toxic hydrogen sulfide (H2S) donor in vitro and in vivo. Stable under acidic and basic conditions but in the presence of bicarbonate liberates the gasotransmitter H2S and glycine. In cells it enhances cGMP formation and in mouse aortic rings promotes vasorelaxation. Cardiopotective agent.
MDL:
MFCD19300630
Molecular Formula:
C2H5NOS
Molecular Weight:
91.1
Package Type:
Vial
Product Description:
Non-toxic hydrogen sulfide (H2S) donor in vitro and in vivo. Stable under acidic and basic conditions but in the presence of bicarbonate liberates the gasotransmitter H2S and glycine. In cells it enhances cGMP formation and in mouse aortic rings promotes vasorelaxation. Cardioprotective agent.
Purity:
>98% (NMR)
SMILES:
NCC(S)=O
Solubility Chemicals:
Soluble in DMSO (10mg/ml) or water.
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
Characterization of thioglycine, a water-soluble hydrogen sulfide (H2S) donor: Z. Zhou, et al.; Vasc. Pharmacol. 56, 356 (2012) | Thioglycine and L-thiovaline: biologically active H2S-donors: Z. Zhou, et al. Bioorg. Med. Chem. 20, 2675 (2012) | Thioglycine, a slow-releasing H2S donor, exerts cardioprotection in anesthetized rabbits through activation of Akt kinase: S.I. Bibli, et al.; Eur. Heart J. 34 (Suppl. 1), P5535 (2013) | Hydrogen sulfide (H2S) releasing agents: chemistry and biological applications: Y. Zhao, et al.; Chem. Commun. 50, 11788 (2014)
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