6-Carboxy-4'5'-dichloro-2' 7'-dimethoxyfluorescein succinimidyl ester
| Code | Size | Price |
|---|
| CDX-C0098-M005 | 5 mg | £304.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
BI
Storage:
Short Term: -20°C . Long Term: -20°C
Documents
Further Information
Alternate Names/Synonyms:
6-JOE, SE; 2,5-Dioxo-1-pyrrolidinyl 4?,5?-Dichloro-3?,6?-dihydroxy-2?,7?-dimethoxy-3-oxospiro[isobenzofuran-1(3H),9?-[9H]xanthene]-6-carboxylate
Appearance:
Orange solid.
CAS:
113394-23-3
EClass:
32160000
Form (Short):
solid
Handling Advice:
Keep cool and dry.Protect from light and moisture.
InChi:
InChI=1S/C27H17Cl2NO11/c1-37-15-8-13-23(19(28)21(15)33)39-24-14(9-16(38-2)22(34)20(24)29)27(13)12-7-10(3-4-11(12)26(36)40-27)25(35)41-30-17(31)5-6-18(30)32/h3-4,7-9,33-34H,5-6H2,1-2H3
InChiKey:
UUVBVONAGUSCCH-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 113394-23-3. Formula: C27H17Cl2NO11. MW: 602.34. Synthetic. Amine-reactive fluorescent probe. A conventional fluorophore predominantly used in automated DNA sequencing. It is also used to label nucleotides. Characterized by an intermediate-wavelength spectra, high quantum yield, and low pH sensitivity in the physiological range. Has a similar absorption and emission spectra to those of rhodamine 6G. Spectral Data: lambdaex 520nm, lambdaem550 nm in Buffer pH 12; lambdaex 520nm, lambdaem 548nm in DMSO.
MDL:
MFCD01311845
Molecular Formula:
C27H17Cl2NO11
Molecular Weight:
602.34
Package Type:
Vial
Product Description:
Amine-reactive fluorescent probe. A conventional fluorophore predominantly used in automated DNA sequencing. It is also used to label nucleotides. Characterized by an intermediate-wavelength spectra, high quantum yield, and low pH sensitivity in the physiological range. Has a similar absorption and emission spectra to those of rhodamine 6G. Spectral Data: lambdaex 520nm, lambdaem550 nm in Buffer pH 12; lambdaex 520nm, lambdaem 548nm in DMSO.
Purity:
>80% (TLC)
SMILES:
O=C(C1=C2C=C(C(ON3C(CCC3=O)=O)=O)C=C1)OC42C5=C(C(Cl)=C(O)C(OC)=C5)OC6=C(Cl)C(O)=C(OC)C=C64
Solubility Chemicals:
Soluble in DMSO, DMF or methanol.
Source / Host:
Synthetic.
Transportation:
Non-hazardous
UNSPSC Category:
Fluorescent Reagents
UNSPSC Number:
41105331
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
(1) F.F. Chehab & Y.W. Kann; PNAS 86, 9178 (1989) | (2) S. Carson, et al.; Anal. Chem. 65, 3219 (1993) | (3) S.C. Hung, et al.; Anal. Biochem. 238, 165 (1996) | (4) A.N. Glazer & R.A. Mathies; Curr. Opin. Biotechnol. 8, 94 (1997) | (5) M. Hahn, et al.; Electrophoresis 22, 2691 (2001) | (6) K. Petersen, et al.; Mol. Cell Probes 18, 117 (2004) | (7) I.M. Mackay; Clin. Microbiol. Infect. 3, 190 (2004) | (8) L.J. Kricka; Ann. Clin. Biochem. 39, 114 (2002)