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6-(Fluorescein-5-carboxamido)hexanoic acid N-succinimidyl ester

Product Code:
 
CDX-F0035
Product Group:
 
Dyes, Stains, and Probes
Supplier:
 
Chemodex
Regulatory Status:
 
RUO
Shipping:
 
Ambient
Storage:
 
Short Term: -20°C. Long Term: -20°C
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Chemical Structure
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Chemical Structure

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CDX-F0035-M01010 mg£230.00
Quantity:
CDX-F0035-M02525 mg£450.00
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Further Information

Alternate Names/Synonyms:
6-(Fluorescein-5-carboxamido)hexanoicacid N-succinimidyl ester; 5-FAM-X, SE
Appearance:
Orange powder.
CAS:
148356-00-7
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Handling Advice:
Keep cool and dry.Protect from light and moisture.
Hazards:
H315, H319, H335
InChi:
InChI=1S/C31H26N2O10/c34-18-6-9-21-24(15-18)42-25-16-19(35)7-10-22(25)29(21)20-8-5-17(14-23(20)31(40)41)30(39)32-13-3-1-2-4-28(38)43-33-26(36)11-12-27(33)37/h5-10,14-16,34H,1-4,11-13H2,(H,32,39)(H,40,41)
InChiKey:
GQROVDGSBTYULQ-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 148356-00-7. Formula: C31H26N2O10. MW: 586.55. Synthetic. Amine-reactive fluorescent probe for introducing a fluorescein label at a nucleophilic residue of a target molecule. This fluorescein labeling reagent has an added (X) spacer to improve accessibility of the reactive group by nucleophiles in preparation of bioconjugates. The reactive N-hydroxysuccinimide (NHS) group can be used for easy attachment to proteins or amine containing nucleotides using simple procedures. Spectral properties: lambdaex 490nm; lambdaem 514nm in DMF (pH 8.2) and lambdaex 491nm; lambdaem 515nm in 0.1 M Tris pH 9.0.
MDL:
MFCD00269767
Molecular Formula:
C31H26N2O10
Molecular Weight:
586.55
Package Type:
Vial
Precautions:
P261, P305, P351, P338
Product Description:
Amine-reactive fluorescent probe for introducing a fluorescein label at a nucleophilic residue of a target molecule. This fluorescein labeling reagent has an added (X) spacer to improve accessibility of the reactive group by nucleophiles in preparation of bioconjugates. The reactive N-hydroxysuccinimide (NHS) group can be used for easy attachment to proteins or amine containing nucleotides using simple procedures. Spectral properties: lambdaex 490nm; lambdaem 514nm in DMF (pH 8.2) and lambdaex 491nm; lambdaem 515nm in 0.1 M Tris pH 9.0.
Purity:
>95% (HPLC)
Signal word:
Warning
SMILES:
OC1=CC2=C(C(C3=CC=C(C(NCCCCCC(ON4C(CCC4=O)=O)=O)=O)C=C3C(O)=O)=C(C=C5)C(O2)=CC5=O)C=C1
Solubility Chemicals:
Soluble in DMSO, DMF or methanol.
Source / Host:
Synthetic.
Transportation:
Non-hazardous
UNSPSC Category:
Fluorescent Reagents
UNSPSC Number:
41105331
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.

References

(1) G.P. Jamieson, et al.; Cytometry 14, 32 (1993) | (2) K.A. Cruickshank; Anal. Biochem. 269, 21 (1999) | (3) J.J. MacLean, et al.; Biophys. J. 78, 1441 (2000) | (4) W.C. Cooper, et al.; Biophys. J. 78, 1449 (2000) | (5) M.P. Gygi, et al.; Nucleic Acids Res. 30, 2790 (2002)