D-(-)-Ribose
| Code | Size | Price |
|---|
| CDX-R0065-G025 | 25 g | £59.00 |
Quantity:
| CDX-R0065-G100 | 100 g | £89.00 |
Quantity:
| CDX-R0065-G250 | 250 g | £181.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
Short Term: +20°C. Long Term: +4°C
Documents
Further Information
Alternate Names/Synonyms:
(2R,3R,4R)-2,3,4,5-Tetrahydroxypentanal; Ribose
Appearance:
White to off-white powder.
CAS:
50-69-1
EClass:
32160000
Form (Short):
liquid
Handling Advice:
Keep cool and dry.Protect from light and moisture.
InChi:
InChI=1S/C5H10O5/c6-1-3(8)5(10)4(9)2-7/h1,3-5,7-10H,2H2/t3-,4+,5-/m0/s1
InChiKey:
PYMYPHUHKUWMLA-LMVFSUKVSA-N
Long Description:
Chemical. CAS: 50-69-1. Formula: C5H10O5. MW: 150.13. Synthetic. Aldopentose monosaccharide that is phosphorylated into D-ribose 5-phosphate by ribokinase. D-ribose-5-phosphate supports the biosynthesis of the amino acids tryptophan and histidine, and is a component in the pentose phosphate pathway. D-ribose is present in all living cells and their microenvironments and is a key component of numerous biomolecules involved in many important metabolic pathways. It also participates in the glycation of proteins producing advanced glycation end products (AGEs) that lead to cell dysfunction and death. Ribosylation, has been shown to cause protein aggregation in vitro and in vivo. Has demonstrated significant enhancing abilities in replenishing deficient cellular energy levels following myocardial ischemia, improving depressed function in numerous animal investigations and showing cellular protection during oxidative stress. D-Ribose is used as a supplement in cell culture and as a building block for synthesis.
MDL:
MFCD00135453
Molecular Formula:
C5H10O5
Molecular Weight:
150.13
Package Type:
Vial
Product Description:
Aldopentose monosaccharide that is phosphorylated into D-ribose 5-phosphate by ribokinase. D-ribose-5-phosphate supports the biosynthesis of the amino acids tryptophan and histidine, and is a component in the pentose phosphate pathway. D-ribose is present in all living cells and their microenvironments and is a key component of numerous biomolecules involved in many important metabolic pathways. It also participates in the glycation of proteins producing advanced glycation end products (AGEs) that lead to cell dysfunction and death. Ribosylation, has been shown to cause protein aggregation in vitro and in vivo. Has demonstrated significant enhancing abilities in replenishing deficient cellular energy levels following myocardial ischemia, improving depressed function in numerous animal investigations and showing cellular protection during oxidative stress. D-Ribose is used as a supplement in cell culture and as a building block for synthesis.
Purity:
>98% (HPLC)
SMILES:
O=C([H])[C@@H]([C@@H]([C@@H](CO)O)O)O
Solubility Chemicals:
Soluble in water.
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at +4°C.
References
(1) L.M. Shecterle, et al.; Recent Pat. Cardiovasc. Drug Discov. 5, 138 (2010) | (2) P. Addis, et al.; J. Diet. Suppl. 9, 178 (2012) | (3) Y. Wei, et al.; Biochim. Biophys. Acta 1820, 488 (2012) | (4) N. Minakawa & A. Matsuda; Curr. Protoc. Nucleic Acid Chem. 59, 14 (2014)
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