Folic acid
| Code | Size | Price |
|---|
| CDX-F0230-G025 | 25 g | £65.00 |
Quantity:
| CDX-F0230-G100 | 100 g | £188.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
Short Term: +20°C. Long Term: +4°C
Documents
Further Information
Alternate Names/Synonyms:
Vitamin Bc; Vitamin Be; Vitamin B9; NSC 3073; PteGlu; Pteroyl-L-glutamic acid; Pteroylglutamic acid; Vitamin M; N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid; Pteroylmonoglutamic acid
Appearance:
Yellow to orange crystalline powder.
CAS:
59-30-3
EClass:
32160000
Form (Short):
liquid
Handling Advice:
Keep cool and dry.Protect from light and moisture.
InChi:
InChI=1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1
InChiKey:
OVBPIULPVIDEAO-LBPRGKRZSA-N
Long Description:
Chemical. CAS: 59-30-3. Formula: C19H19N7O6. MW: 441.4. Synthetic. Folic acid, also known as folate, is a B vitamin is an essential nutritional component of the human diet. It is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis, and for preventing changes to DNA, and consequently cancer. It is especially important during periods of frequent cell division and growth, such as infancy and pregnancy. Folate is needed to carry one-carbon groups for methylation reactions and nucleic acid synthesis. Folic acid deficiency hinders DNA synthesis and cell division, affecting hematopoietic cells and neoplasms the most because of their greater frequency of cell division. Both adults and children need folate to make normal red and white blood cells and prevent anemia. Deficiency of folic acid in pregnant women has been implicated in neural tube defects (NTD).
MDL:
MFCD00079305
Molecular Formula:
C19H19N7O6
Molecular Weight:
441.4
Package Type:
Vial
Product Description:
Folic acid, also known as folate, is a B vitamin is an essential nutritional component of the human diet. It is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis, and for preventing changes to DNA, and consequently cancer. It is especially important during periods of frequent cell division and growth, such as infancy and pregnancy. Folate is needed to carry one-carbon groups for methylation reactions and nucleic acid synthesis. Folic acid deficiency hinders DNA synthesis and cell division, affecting hematopoietic cells and neoplasms the most because of their greater frequency of cell division. Both adults and children need folate to make normal red and white blood cells and prevent anemia. Deficiency of folic acid in pregnant women has been implicated in neural tube defects (NTD).
Purity:
>95% (HPLC)
SMILES:
O=C(O)[C@](NC(C1=CC=C(NCC2=NC3=C(N=C2)N=C(N)NC3=O)C=C1)=O)([H])CCC(O)=O
Solubility Chemicals:
Soluble in 1M NaOH (50 mg/ml), diluted acids or allkaline solutions. Slightly soluble in water (1.6mg/ml) or methanol.
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at +4°C.
References
(1) B. Kamen; Semin. Oncol. 24, S18-30 (1997) | (2) Y.I. Kim; Nutr. Rev. 57, 314 (1999) | (3) S.W. Choi & J.B. Mason; J. Nutr. 130, 129 (2000) | (4) P. Mastroiacovo & E. Leoncini; Biofactors 37, 272 (2011) | (5) S.Y. Taylor, et al.; Eur. J. Pharmacol. 714, 193 (2013) | (6) N. Laurieri, et al.; PLoS One 9, e96370 (2014) | (7) S.Y. Hwang, et al.; Int. J. Mol. Med. 36, 1073 (2015) | (8) H.N. Moussa, et al.; Future Sci. OA. 2, 2 (2016)