D-Mannitol
| Code | Size | Price |
|---|
| CDX-M0228-G500 | 500 g | £57.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
Short Term: +20°C. Long Term: +20°C
Documents
Further Information
Alternate Names/Synonyms:
Mannite; Osmitrol; Cordycepic acid
Appearance:
White crystalline powder.
CAS:
69-65-8
EClass:
32160000
Form (Short):
solid
Handling Advice:
Protect from light and moisture.
InChi:
InChI=1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1
InChiKey:
FBPFZTCFMRRESA-KVTDHHQDSA-N
Long Description:
Chemical. CAS: 69-65-8. Formula: C6H14O6. MW: 182.17. Synthetic. Sugar alcohol that can be used as an inert osmotic control substance. The uptake and phosphorylation of D-Mannitol is catalyzed by the mannitol-specific phosphoenolpyruvate-dependent phosphotransferase systems (PTS). Used in pharmacy as excipient and diluent for solids and liquids and in analytical chemistry for boron determinations. It is used as an anticaking and free-flow agent, flavoring agent, lubricant and release agent, stabilizer and thickener and nutritive sweetener in the food industry. Used in sweetness inhibition studies. Can interact with neutrophils and monocytes. Experiments have shown that it is able to decrease neutrophil apoptosis in vitro. Can lower fat digestibility and body fat accumulation in rats, as well as upregulate monocyte HLA-DR, monocyte and neutrophil CD11b.
MDL:
MFCD00064287
Molecular Formula:
C6H14O6
Molecular Weight:
182.17
Package Type:
Vial
Product Description:
Sugar alcohol that can be used as an inert osmotic control substance. The uptake and phosphorylation of D-Mannitol is catalyzed by the mannitol-specific phosphoenolpyruvate-dependent phosphotransferase systems (PTS). Used in pharmacy as excipient and diluent for solids and liquids and in analytical chemistry for boron determinations. It is used as an anticaking and free-flow agent, flavoring agent, lubricant and release agent, stabilizer and thickener and nutritive sweetener in the food industry. Used in sweetness inhibition studies. Can interact with neutrophils and monocytes. Experiments have shown that it is able to decrease neutrophil apoptosis in vitro. Can lower fat digestibility and body fat accumulation in rats, as well as upregulate monocyte HLA-DR, monocyte and neutrophil CD11b.
Purity:
>97% (HPLC)
SMILES:
OC[C@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O
Solubility Chemicals:
Soluble in water, alcohol or glycerol.
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at +20°C.
References
(1) Q. Wang, et al.; Drug Metab. Dispos. 36, 2244 (2008) | (2) M. Turina, et al.; Inflammation 31, 74 (2008) | (3) A. Nishiyama, et al.; J. Nutr. Sci. Vitaminol. 55, 242 (2009) | (4) B.C. Saha & F.M. Racine; Appl. Microbiol. Biotechnol. 89, 879 (2011) | (5) A. Kumar, et al.; J. Clin. Diagn. Res. 8, GE01 (2014) | (6) H.L. Ohrem, et al.; Pharm. Dev. Technol. 19, 257 (2014) | (7) P. Andre & F. Villain; Int. J. Cosmet. Sci. (2016)