Dcr-1 Antibody
| Code | Size | Price |
|---|
| PSI-60-630-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: C. Elegans
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Endoribonuclease dcr-1, 3126-, dcr-1
Application Note:
For WB starting dilution is: 1:1000
Background:
The Dcr-1 gene encodes a bidentate ribonuclease that is homologous to E. coli RNAse III. Dcr-1 is required both for RNA interference and for synthesis of small developmental RNAs. Dcr-1 interacts in vivo with RDE-4, a double-stranded RNA (dsRNA) binding protein required for RNAi that interacts with trigger dsRNAs and may function to deliver dsRNAs to Dcr-1 for endonucleolytic processing.
Background References:
- Duchaine TF, et al. 2006. Cell 124:343-354.
- Denli AM, et al. 2004. Nature 432:231-235.
- Tabara H, et al. 2002. Cell 109:861-871.
- Grishok A, et al. 2001. Cell 106:23-34.
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This Dcr-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1068-1097 amino acids from the Central region of human Dcr-1.
NCBI Gene ID #:
176138
NCBI Official Name:
Endoribonuclease dcr-1
NCBI Official Symbol:
dcr-1
NCBI Organism:
Caenorhabditis elegans
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
218 kDa
Protein Accession #:
P34529
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Swissprot #:
P34529
User NOte:
Optimal dilutions for each application to be determined by the researcher.