gp120 Antibody
| Code | Size | Price |
|---|
| PSI-8677-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-8677-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human immunodeficiency virus (HIV)
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
gp120 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
gp120 Antibody: Envelope glycoprotein gp160
Application Note:
gp120 antibody can be used for Western blot at 1 - 2 μg/mL.
Background:
Human immunodeficiency virus type 1 (HIV-1) entry into target cells is directed by the envelope (Env) glycoproteins, which are present on the surface of HIV-1 virion or infected cells in the form of trimers consisting of gp120/gp41 complexes. The surface subunit, gp120, initiates the entry process by interacting sequentially with the CD4 receptor and a co-receptor CCR5 or CXCR4, thereby inducing a conformational change that allows the transmembrane (TM) gp41 subunit to mediate fusion between viral and target cell membranes. Cleavage of Env into its gp120 and gp41 components is necessary for activation of its fusogenic activity.
Buffer:
gp120 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
gp120 antibody was raised against a peptide corresponding to 15 amino acids near the center of HIV-1 gp120.
NCBI Gene ID #:
155971
NCBI Official Name:
env
NCBI Official Symbol:
gp120
NCBI Organism:
HIV-1
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Predicted: 120 kDa
Observed: 120 kDa
Observed: 120 kDa
Protein Accession #:
AAB05604
Protein GI Number:
1465781
Purification:
gp120 Antibody is affinity chromatography purified via peptide column.
Research Area:
Infectious Disease
Swissprot #:
P04578
User NOte:
Optimal dilutions for each application to be determined by the researcher.