POU6F2 Antibody
| Code | Size | Price |
|---|
| PSI-56-320-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
POU domain, class 6, transcription factor 2, Retina-derived POU domain factor 1, RPF-1, POU6F2, RPF1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the POU protein family
characterized by the presence of a bipartite DNA binding domain,
consisting of a POU-specific domain and a homeodomain, separated by
a variable polylinker. The DNA binding domain may bind to DNA as
monomers or as homo- and/or heterodimers, in a sequence-specific
manner. The POU family members are transcriptional regulators, many
of which are known to control cell type-specific differentiation
pathways. This gene is a tumor suppressor involved in Wilms tumor
(WT) predisposition. Alternatively spliced transcript variants
encoding distinct isoforms have been found for this gene.
Background References:
- Anney, R., et al. Hum. Mol. Genet. 19(20):4072-4082(2010)
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)
- Di Renzo, F., et al. J. Pediatr. Hematol. Oncol. 28(12):791-797(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This POU6F2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 34-61 amino acids from the N-terminal region of human POU6F2.
NCBI Gene ID #:
11281
NCBI Official Name:
POU domain, class 6, transcription factor 2
NCBI Official Symbol:
POU6F2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
73 kDa
Protein Accession #:
P78424
Protein GI Number:
327478564
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer
Swissprot #:
P78424
User NOte:
Optimal dilutions for each application to be determined by the researcher.