MUM1 Antibody

ProSci
Product Code: PSI-59-391
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-59-391-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

1 / 1
Western blot analysis in CEM cell line lysates (35ug/lane).

Western blot analysis in CEM cell line lysates (35ug/lane).

Further Information

Additional Names:
PWWP domain-containing protein MUM1, Mutated melanoma-associated antigen 1, MUM-1, Protein expandere, MUM1, EXPAND1
Application Note:
For WB starting dilution is: 1:1000
Background:
Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.
Background References:
  • Huen, M.S., et al. Mol. Cell 37(6):854-864(2010)
  • Matsuoka, S., et al. Science 316(5828):1160-1166(2007)
  • Coulie, P.G., et al. Proc. Natl. Acad. Sci. U.S.A. 92(17):7976-7980(1995)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MUM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 671-699 amino acids from the C-terminal region of human MUM1.
NCBI Gene ID #:
84939
NCBI Official Name:
PWWP domain-containing protein MUM1
NCBI Official Symbol:
MUM1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
79 kDa
Protein Accession #:
Q2TAK8
Protein GI Number:
259016340
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer
Swissprot #:
Q2TAK8
User NOte:
Optimal dilutions for each application to be determined by the researcher.