DYRK1B Antibody
| Code | Size | Price |
|---|
| PSI-58-681-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Dual specificity tyrosine-phosphorylation-regulated kinase 1B, Minibrain-related kinase, Mirk protein kinase, DYRK1B, MIRK
Application Note:
For WB starting dilution is: 1:1000
Background:
DYRK1B is a member of the DYRK family of protein kinases.
DYRK1B contains a bipartite nuclear localization signal and is
found mainly in muscle and testis. The protein is proposed to be
involved in the regulation of nuclear functions. Three isoforms of
DYRK1B have been identified differing in the presence of two
alternatively spliced exons within the catalytic domain. [provided
by RefSeq].
Background References:
- Lauth, M., et al. Nat. Struct. Mol. Biol. 17(6):718-725(2010)
- Yang, C., et al. Carcinogenesis 31(4):552-558(2010)
- Jin, K., et al. J. Biol. Chem. 284(34):22916-22925(2009)
- Deng, X., et al. Cancer Res. 69(8):3317-3324(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This DYRK1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 377-405 amino acids from the Central region of human DYRK1B.
NCBI Gene ID #:
9149
NCBI Official Name:
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
NCBI Official Symbol:
DYRK1B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
69 kDa
Protein Accession #:
Q9Y463
Protein GI Number:
9296963
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer
Swissprot #:
Q9Y463
User NOte:
Optimal dilutions for each application to be determined by the researcher.