ANP32C Antibody
Code | Size | Price |
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PSI-59-136-400ul | 400ul | £626.00 |
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Acidic leucine-rich nuclear phosphoprotein 32 family member C, Phosphoprotein 32-related protein 1, Tumorigenic protein pp32r1, ANP32C, PP32R1
Application Note:
For WB starting dilution is: 1:1000
Background:
Phosphoprotein 32 (PP32) is a tumor suppressor that can
inhibit several types of cancers, including prostate and breast
cancers. The protein encoded by this gene is one of at least two
proteins that are similar in amino acid sequence to PP32 and are
part of the same acidic nuclear phosphoprotein gene family.
However, unlike PP32, the encoded protein is tumorigenic. The tumor
suppressor function of PP32 has been localized to a 25 amino acid
region that is divergent between PP32 and the protein encoded by
this gene. This gene does not contain introns. [provided by
RefSeq].
Background References:
- Matilla, A., et al. Cerebellum 4(1):7-18(2005)
- Kochevar, G.J., et al. Hum. Mutat. 23(6):546-551(2004)
- Fan, Z., et al. Nat. Immunol. 4(2):145-153(2003)
- Kadkol, S.S., et al. Breast Cancer Res. Treat. 68(1):65-73(2001)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ANP32C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 130-158 amino acids from the Central region of human ANP32C.
NCBI Gene ID #:
23520
NCBI Official Name:
Acidic leucine-rich nuclear phosphoprotein 32 family member C
NCBI Official Symbol:
ANP32C
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
27 kDa
Protein Accession #:
O43423
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer
Swissprot #:
O43423
User NOte:
Optimal dilutions for each application to be determined by the researcher.