MCC Antibody
| Code | Size | Price |
|---|
| PSI-59-060-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Colorectal mutant cancer protein, Protein MCC, MCC
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene is a candidate colorectal tumor suppressor gene
that is thought to negatively regulate cell cycle progression. The
orthologous gene in the mouse expresses a phosphoprotein associated
with the plasma membrane and membrane organelles, and
overexpression of the mouse protein inhibits entry into S phase.
Multiple transcript variants encoding different isoforms have been
found for this gene.
Background References:
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010)
- Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010)
- Arnaud, C., et al. FEBS Lett. 583(14):2326-2332(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MCC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 473-501 amino acids from the Central region of human MCC.
NCBI Gene ID #:
4163
NCBI Official Name:
Colorectal mutant cancer protein
NCBI Official Symbol:
MCC
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
93 kDa
Protein Accession #:
P23508
Protein GI Number:
317373352
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer
Swissprot #:
P23508
User NOte:
Optimal dilutions for each application to be determined by the researcher.