TBX2 Antibody

ProSci
Product Code: PSI-59-016
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-59-016-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in Hela cell line lysates (35ug/lane).

Western blot analysis in Hela cell line lysates (35ug/lane).

Further Information

Additional Names:
T-box transcription factor TBX2, T-box protein 2, TBX2
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent. Transcript heterogeneity due to alternative polyadenylation has been noted for this gene.
Background References:
  • Vance, K.W., et al. Mol. Biol. Cell 21(15):2770-2779(2010)
  • Radio, F.C., et al. Am. J. Med. Genet.152A (8), 2061-2066 (2010) :
  • Kottgen, A., et al. Nat. Genet. 42(5):376-384(2010)
  • Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TBX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 414-442 amino acids from the Central region of human TBX2.
NCBI Gene ID #:
6909
NCBI Official Name:
T-box transcription factor TBX2
NCBI Official Symbol:
TBX2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
75 kDa
Protein Accession #:
Q13207
Protein GI Number:
294862490
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer
Swissprot #:
Q13207
User NOte:
Optimal dilutions for each application to be determined by the researcher.