NUDCD1 Antibody

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ProSci
Product Code: PSI-57-947
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-57-947-400ul400ul£626.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in A549 cell line lysates (35ug/lane).
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Western blot analysis in A549 cell line lysates (35ug/lane).

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Further Information

Additional Names:
NudC domain-containing protein 1, Chronic myelogenous leukemia tumor antigen 66, Tumor antigen CML66, NUDCD1 (HGNC:24306)
Application Note:
For WB starting dilution is: 1:1000
Background:
NUDCD1 (CML66) contains 1 CS domain. It may play an oncogenic role in ways of favoring tumor cells proliferation, invasion and metastasis-associated with multiple pathways. NUDCD1 is expressed in leukemias and a variety of solid tumor cell lines. Northern blot analysis showed expression in normal tissues restricted to testis and heart, and no expression was found in hematopoietic tissues.
Background References:
  • Wang, Q., et al. Cancer Lett. 269(1):127-138(2008)
  • Jin, S., et al. Cancer Sci. 99(8):1670-1678(2008)
  • Yan, Y., et al. J. Immunol. 172(1):651-660(2004)
  • Yang, X.F., et al. Proc. Natl. Acad. Sci. U.S.A. 98(13):7492-7497(2001)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This NUDCD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 194-223 amino acids from the Central region of human NUDCD1.
NCBI Gene ID #:
84955
NCBI Official Name:
NudC domain-containing protein 1
NCBI Official Symbol:
NUDCD1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
67 kDa
Protein Accession #:
Q96RS6
Protein GI Number:
296439243
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer
Swissprot #:
Q96RS6
User NOte:
Optimal dilutions for each application to be determined by the researcher.