DLEC1 Antibody

ProSci
Product Code: PSI-58-381
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-58-381-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in NCI-H460 cell line lysates (35ug/lane).

Western blot analysis in NCI-H460 cell line lysates (35ug/lane).

Further Information

Additional Names:
Deleted in lung and esophageal cancer protein 1, Deleted in lung cancer protein 1, DLC-1, DLEC1 {ECO:0000312|EMBL:BAA776241}
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene contains 37 exons, spans approximately 59-kb, and is located in the 3p22-p21.3 chromosomal segment that is commonly deleted in various carcinomas. Several alternatively spliced transcripts have been observed that contain disrupted coding regions and likely encode nonfunctional proteins. Aberrant transcription of this gene may be involved in carcinogenesis of the lung, esophagus, and kidney.
Background References:
  • Zhang, Q., et al. J. Urol. 184(2):731-737(2010)
  • Zhang, Y., et al. Clin Lung Cancer 11(4):264-270(2010)
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Al Sarakbi, W., et al. Anticancer Res. 30(4):1079-1082(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This DLEC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 263-292 amino acids from the N-terminal region of human DLEC1.
NCBI Gene ID #:
9940
NCBI Official Name:
Deleted in lung and esophageal cancer protein 1
NCBI Official Symbol:
DLEC1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
196 kDa
Protein Accession #:
Q9Y238
Protein GI Number:
296434480
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer
Swissprot #:
Q9Y238
User NOte:
Optimal dilutions for each application to be determined by the researcher.