TCL1A Antibody

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ProSci
Product Code: PSI-61-025
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-61-025-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Flow Cytometry
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Flow cytometric analysis of Ramos cells using TCL1A Antibody (green) compared to an isotype control of rabbit IgG(blue). Antibody was diluted at 1:25 dilution. An Alexa Fluor 488 goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody.
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Western blot analysis of lysate from Ramos cell line, using TCL1A Antibody at 1:1000.
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Flow cytometric analysis of Ramos cells using TCL1A Antibody (green) compared to an isotype control of rabbit IgG(blue). Antibody was diluted at 1:25 dilution. An Alexa Fluor 488 goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody.
Western blot analysis of lysate from Ramos cell line, using TCL1A Antibody at 1:1000.

Documents

Further Information

Additional Names:
T-cell leukemia/lymphoma protein 1A, Oncogene TCL-1, Oncogene TCL1, Protein p14 TCL1, TCL1A, TCL1
Application Note:
For FACS starting dilution is: 1:25

For WB starting dilution is: 1:1000
Background:
Enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. Promotes nuclear translocation of AKT1. Enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival.
Background References:
  • Virgilio L.,et al.Proc. Natl. Acad. Sci. U.S.A. 91:12530-12534(1994).
  • Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
  • Fu T.-B.,et al.Cancer Res. 54:6297-6301(1994).
  • Laine J.,et al.Mol. Cell 6:395-407(2000).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TCL1A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 32-66 amino acids from the Central region of human TCL1A.
NCBI Gene ID #:
8115
NCBI Official Name:
T-cell leukemia/lymphoma protein 1A
NCBI Official Symbol:
TCL1A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
13 kDa
Protein Accession #:
P56279
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer
Swissprot #:
P56279
User NOte:
Optimal dilutions for each application to be determined by the researcher.