TGIF2 Antibody
| Code | Size | Price |
|---|
| PSI-58-005-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Flow Cytometry
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Homeobox protein TGIF2, 5'-TG-3'-interacting factor 2, TGF-beta-induced transcription factor 2, TGFB-induced factor 2, TGIF2
Application Note:
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Background:
The protein encoded by this gene is a DNA-binding homeobox
protein and a transcriptional repressor. The encoded protein
appears to repress transcription by recruiting histone deacetylases
to TGF beta-responsive genes. This gene is amplified and
overexpressed in some ovarian cancers, and mutations in this gene
can cause holoprosencephaly.
Background References:
- Watanabe, T., et al. Jpn. J. Cancer Res. 93(10):1114-1122(2002)
- Deloukas, P., et al. Nature 414(6866):865-871(2001)
- Melhuish, T.A., et al. J. Biol. Chem. 276(34):32109-32114(2001)
- Imoto, I., et al. Biochem. Biophys. Res. Commun. 276(1):264-270(2000)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TGIF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-199 amino acids from the C-terminal region of human TGIF2.
NCBI Gene ID #:
100527943, 60436
NCBI Official Name:
Homeobox protein TGIF2
NCBI Official Symbol:
TGIF2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
26 kDa
Protein Accession #:
Q9GZN2
Protein GI Number:
27805750
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer
Swissprot #:
Q9GZN2
User NOte:
Optimal dilutions for each application to be determined by the researcher.