MYB Antibody
| Code | Size | Price |
|---|
| PSI-57-402-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Transcriptional activator Myb, Proto-oncogene c-Myb, MYB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes a transcription factor that is a member
of the MYB family of transcription factor genes. The protein
contains three domains, an N-terminal DNA-binding domain, a central
transcriptional activation domain and a C-terminal domain involved
in transcriptional repression. This protein plays an essential role
in the regulation of hematopoiesis and may play a role in
tumorigenesis. Alternative splicing results in multiple transcript
variants.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Tanno, B., et al. J. Biol. Chem. 285(38):29434-29445(2010)
- Melen, E., et al. J. Allergy Clin. Immunol. 126(3):631-637(2010)
- Stenman, G., et al. Cell Cycle 9(15):2986-2995(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MYB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 419-448 amino acids from the Central region of human MYB.
NCBI Gene ID #:
4602
NCBI Official Name:
Transcriptional activator Myb
NCBI Official Symbol:
MYB
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
72 kDa
Protein Accession #:
P10242
Protein GI Number:
2815504
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer
Swissprot #:
P10242
User NOte:
Optimal dilutions for each application to be determined by the researcher.