MAGEC1 Antibody
| Code | Size | Price |
|---|
| PSI-62-156-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Melanoma-associated antigen C1, Cancer/testis antigen 71, CT71, MAGE-C1 antigen, MAGEC1
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For IHC-P starting dilution is: 1:50~100
Background:
MAGEC1 is a member of the melanoma antigen gene (MAGE) family. The proteins of this family are tumor-specific antigens that can be recognized by autologous cytolytic T lymphocytes. This protein contains a large number of unique short repetitive sequences in front of the MAGE-homologous sequence, thus is about 800 residues longer than the other MAGE proteins. This gene is expressed in a significant proportion of tumors of various histological types, whereas it is silent in normal tissues, except testis. The function of this gene is unknown.
Background References:
- Jungbluth, A.A., et al., Int. J. Cancer 99(6):839-845 (2002).
- Chen, Y.T., et al., Proc. Natl. Acad. Sci. U.S.A. 95(12):6919-6923 (1998).
- Lucas, S., et al., Cancer Res. 58(4):743-752 (1998).
- Lim, S.H., et al., Eur. J. Haematol. 67 (5-6), 332-334 (2001).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MAGEC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 849-880 amino acids from the C-terminal region of human MAGEC1.
NCBI Gene ID #:
9947
NCBI Official Name:
Melanoma-associated antigen C1
NCBI Official Symbol:
MAGEC1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
124 kDa
Protein Accession #:
O60732
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cancer
Swissprot #:
O60732
User NOte:
Optimal dilutions for each application to be determined by the researcher.