RARRES1 Antibody

ProSci
Product Code: PSI-56-875
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-56-875-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in CEM cell line lysates (35ug/lane).
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RARRES1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Western blot analysis in CEM cell line lysates (35ug/lane).
RARRES1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Further Information

Additional Names:
Retinoic acid receptor responder protein 1, Phorbol ester-induced gene 1 protein, PERG-1, RAR-responsive protein TIG1, Tazarotene-induced gene 1 protein, RARRES1, PEIG1, TIG1
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
This gene was identified as a retinoid acid (RA) receptor-responsive gene. It encodes a type 1 membrane protein. The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors. The expression of this gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG island. Alternatively spliced transcript variant encoding distinct isoforms have been observed.
Background References:
  • Wheeler, H.E., et al. PLoS Genet.(10), E1000685 (2009) :
  • Kwok, W.K., et al. Cancer Genet. Cytogenet. 194(1):58-64(2009)
  • Ohnishi, S., et al. Cell Prolif. 42(3):309-316(2009)
  • Son, M.S., et al. Oncol. Res. 17 (11-12), 571-580 (2009) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This RARRES1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-163 amino acids from the C-terminal region of human RARRES1.
NCBI Gene ID #:
5918
NCBI Official Name:
Retinoic acid receptor responder protein 1
NCBI Official Symbol:
RARRES1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
33 kDa
Protein Accession #:
P49788
Protein GI Number:
57014141
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer
Swissprot #:
P49788
User NOte:
Optimal dilutions for each application to be determined by the researcher.