EAPII Antibody
| Code | Size | Price |
|---|
| PSI-55-723-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Fluorescence-activated cell sorting (FACS)
- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Tyrosyl-DNA phosphodiesterase 2, Tyr-DNA phosphodiesterase 2, hTDP2, 314-, 5'-tyrosyl-DNA phosphodiesterase, 5'-Tyr-DNA phosphodiesterase, ETS1-associated protein 2, ETS1-associated protein II, EAPII, TRAF and TNF receptor-associated protein, Tyrosyl-RNA phosphodiesterase, VPg unlinkase, TDP2, EAP2, TTRAP
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Background:
This gene encodes a member of a superfamily of divalent
cation-dependent phosphodiesterases. The encoded protein associates
with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor
associated factors (TRAFs), and inhibits nuclear factor-kappa-B
activation. This protein has sequence and structural similarities
with APE1 endonuclease, which is involved in both DNA repair and
the activation of transcription factors.
Background References:
- Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
- Wang, B.Y., et al. Mol. Biol. Rep. 37(6):2809-2816(2010)
- Iijima, M., et al. Neurology 73(17):1348-1352(2009)
- Cortes Ledesma, F., et al. Nature 461(7264):674-678(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This EAPII antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 246-272 amino acids from the C-terminal region of human EAPII.
NCBI Gene ID #:
51567
NCBI Official Name:
Tyrosyl-DNA phosphodiesterase 2
NCBI Official Symbol:
TDP2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
41 kDa
Protein Accession #:
O95551
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer
Swissprot #:
O95551
User NOte:
Optimal dilutions for each application to be determined by the researcher.